Paralogue Annotation for ANK2 residue 127

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 127
Reference Amino Acid: S - Serine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 127

No paralogue variants have been mapped to residue 127 for ANK2.

ANK2	GNTALHIASLAGQAEVVKVLVKEGANINAQ>S<QNGFTPLYMAAQENHIDVVKYLLENGANQS	157
ANK1	GNTALHIAALAGQDEVVRELVNYGANVNAQ>S<QKGFTPLYMAAQENHLEVVKFLLENGANQN	138
ANK3	GNTALHIASLAGQAEVVKVLVTNGANVNAQ>S<QNGFTPLYMAAQENHLEVVKFLLDNGASQS	167
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See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.S127Y	c.380C>A	Putative Benign			SIFT: deleterious Polyphen: probably damaging
p.S127T	c.379T>A	Putative Benign			SIFT: Polyphen: