Paralogue Annotation for ANK2 residue 166

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 166
Reference Amino Acid: P - Proline
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 166

No paralogue variants have been mapped to residue 166 for ANK2.

ANK2	MAAQENHIDVVKYLLENGANQSTATEDGFT>P<LAVALQQGHNQAVAILLENDTKGKVRLPAL	196
ANK1	MAAQENHLEVVKFLLENGANQNVATEDGFT>P<LAVALQQGHENVVAHLINYGTKGKVRLPAL	177
ANK3	MAAQENHLEVVKFLLDNGASQSLATEDGFT>P<LAVALQQGHDQVVSLLLENDTKGKVRLPAL	206
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See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P166A	c.496C>G	Putative Benign		rs372278263	SIFT: deleterious Polyphen: probably damaging