Paralogue Annotation for ANK2 residue 377

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 377
Reference Amino Acid: H - Histidine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 377

No paralogue variants have been mapped to residue 377 for ANK2.

ANK2	CVKHLLQHKAPVDDVTLDYLTALHVAAHCG>H<YRVTKLLLDKRANPNARALNGFTPLHIACK	407
ANK1	CVRLLLQYDAEIDDITLDHLTPLHVAAHCG>H<HRVAKVLLDKGAKPNSRALNGFTPLHIACK	380
ANK3	CVQLLLQHNVPVDDVTNDYLTALHVAAHCG>H<YKVAKVLLDKKANPNAKALNGFTPLHIACK	409
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.H377Y	c.1129C>T	Putative Benign		rs182536026	SIFT: Polyphen: probably damaging