Paralogue Annotation for ANK2 residue 421

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 421
Reference Amino Acid: G - Glycine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 421

No paralogue variants have been mapped to residue 421 for ANK2.

ANK2	PNARALNGFTPLHIACKKNRIKVMELLVKY>G<ASIQAITESGLTPIHVAAFMGHLNIVLLLL	451
ANK1	PNSRALNGFTPLHIACKKNHVRVMELLLKT>G<ASIDAVTESGLTPLHVASFMGHLPIVKNLL	424
ANK3	PNAKALNGFTPLHIACKKNRIKVMELLLKH>G<ASIQAVTESGLTPIHVAAFMGHVNIVSQLM	453
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See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G421A	c.1262G>C	Putative Benign			SIFT: deleterious Polyphen: possibly damaging