Paralogue Annotation for ANK2 residue 427

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 427
Reference Amino Acid: I - Isoleucine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 427

No paralogue variants have been mapped to residue 427 for ANK2.

ANK2	NGFTPLHIACKKNRIKVMELLVKYGASIQA>I<TESGLTPIHVAAFMGHLNIVLLLLQNGASP	457
ANK1	NGFTPLHIACKKNHVRVMELLLKTGASIDA>V<TESGLTPLHVASFMGHLPIVKNLLQRGASP	430
ANK3	NGFTPLHIACKKNRIKVMELLLKHGASIQA>V<TESGLTPIHVAAFMGHVNIVSQLMHHGASP	459
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I427V	c.1279A>G	Putative Benign			SIFT: Polyphen:
p.I427L	c.1279A>T	Putative Benign			SIFT: Polyphen: