Paralogue Annotation for ANK2 residue 459

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 459
Reference Amino Acid: V - Valine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 459

No paralogue variants have been mapped to residue 459 for ANK2.

ANK2	ESGLTPIHVAAFMGHLNIVLLLLQNGASPD>V<TNIRGETALHMAARAGQVEVVRCLLRNGAL	489
ANK1	ESGLTPLHVASFMGHLPIVKNLLQRGASPN>V<SNVKVETPLHMAARAGHTEVAKYLLQNKAK	462
ANK3	ESGLTPIHVAAFMGHVNIVSQLMHHGASPN>T<TNVRGETALHMAARSGQAEVVRYLVQDGAQ	491
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.V459I	c.1375G>A	Putative Benign		rs375167175	SIFT: tolerated Polyphen: benign