Paralogue Annotation for ANK2 residue 460

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 460
Reference Amino Acid: T - Threonine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 460

No paralogue variants have been mapped to residue 460 for ANK2.

ANK2	SGLTPIHVAAFMGHLNIVLLLLQNGASPDV>T<NIRGETALHMAARAGQVEVVRCLLRNGALV	490
ANK1	SGLTPLHVASFMGHLPIVKNLLQRGASPNV>S<NVKVETPLHMAARAGHTEVAKYLLQNKAKV	463
ANK3	SGLTPIHVAAFMGHVNIVSQLMHHGASPNT>T<NVRGETALHMAARSGQAEVVRYLVQDGAQV	492
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T460A	c.1378A>G	Putative Benign		rs368129159	SIFT: tolerated Polyphen: benign
p.T460I	c.1379C>T	Putative Benign		rs370499460	SIFT: tolerated Polyphen: benign