Paralogue Annotation for ANK2 residue 491

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 491
Reference Amino Acid: D - Aspartate
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 491

No paralogue variants have been mapped to residue 491 for ANK2.

ANK2	NIRGETALHMAARAGQVEVVRCLLRNGALV>D<ARAREEQTPLHIASRLGKTEIVQLLLQHMA	521
ANK1	NVKVETPLHMAARAGHTEVAKYLLQNKAKV>N<AKAKDDQTPLHCAARIGHTNMVKLLLENNA	494
ANK3	NVRGETALHMAARSGQAEVVRYLVQDGAQV>E<AKAKDDQTPLHISARLGKADIVQQLLQQGA	523
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D491N	c.1471G>A	Putative Benign		rs112178659	SIFT: tolerated Polyphen: possibly damaging