Paralogue Annotation for ANK2 residue 745

Residue details

Gene: ANK2
Reference Sequences: LRG: LRG_327, Ensembl variant: ENST00000264366 / ENSP00000264366
Amino Acid Position: 745
Reference Amino Acid: N - Asparagine
Protein Domain: Ankyrin domain region

Paralogue Variants mapped to ANK2 residue 745

No paralogue variants have been mapped to residue 745 for ANK2.

ANK2	TKHGADQDAHTKLGYTPLIVACHYGNVKMV>N<FLLKQGANVNAKTKNGYTPLHQAAQQGHTH	775
ANK1	IKHGVMVDATTRMGYTPLHVASHYGNIKLV>K<FLLQHQADVNAKTKLGYSPLHQAAQQGHTD	748
ANK3	VNQGAHVDAQTKMGYTPLHVGCHYGNIKIV>N<FLLQHSAKVNAKTKNGYTPLHQAAQQGHTH	777
cons	> <

See full Alignment of Paralogues

Known Variants in ANK2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.N745S	c.2234A>G	Putative Benign			SIFT: Polyphen: probably damaging
p.Asn745Ser	c.2234A>G	Unknown			SIFT: Polyphen: