Paralogue Annotation for CACNA1C residue 1170

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1170
Reference Amino Acid: Q - Glutamine
Protein Domain: TM domain 3


Paralogue Variants mapped to CACNA1C residue 1170

No paralogue variants have been mapped to residue 1170 for CACNA1C.



CACNA1CVEISIFFIIYIIIIAFFMMNIFVGFVIVTF>Q<EQGEQE----YKNCELDKNQR------QCV1190
CACNA1AMEMSIFYVVYFVVFPFFFVNIFVALIIITF>Q<EQGDKM----MEEYSLEKNER------ACI1535
CACNA1BMELSIFYVVYFVVFPFFFVNIFVALIIITF>Q<EQGDKV----MSECSLEKNER------ACI1441
CACNA1DVEISIFFIIYIIIVAFFMMNIFVGFVIVTF>Q<EQGEKE----YKNCELDKNQR------QCV1196
CACNA1EMEMSIFYVVYFVVFPFFFVNIFVALIIITF>Q<EQGDKM----MEECSLEKNER------ACI1447
CACNA1FVEISVFFIVYIIIIAFFMMNIFVGFVIITF>R<AQGEQE----YQNCELDKNQR------QCV1161
CACNA1GPWMLLYFISFLLIVAFFVLNMFVGVVVENF>H<KCRQHQEEEEARRREEKRLRRLEKKRRNLM1571
CACNA1HPWMLLYFISFLLIVSFFVLNMFVGVVVENF>H<KCRQHQEAEEARRREEK----------RLR1579
CACNA1IPWMLLYFISFLLIVSFFVLNMFVGVVVENF>H<KCRQHQEAEEARRREEK----------RLR1455
CACNA1SVEMAIFFIIYIILIAFFMMNIFVGFVIVTF>Q<EQGETE----YKNCELDKNQR------QCV1089
SCN10AVYMYLYFVIFIIFGGFFTLNLFVGVIIDNF>N<QQKKKLGGQDIFMTEEQKKYY------NAM1446
SCN11ASLGYIYFVVFIIFGSFFTLNLFIGVIIDNF>N<QQQKKLGGQDIFMTEEQKKYY------NAM1336
SCN1ALYMYLYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKFGGQDIFMTEEQKKYY------NAM1511
SCN2ALYMYLYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKFGGQDIFMTEEQKKYY------NAM1501
SCN3ALYMYLYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKFGGQDIFMTEEQKKYY------NAM1496
SCN4ALYMYLYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKLGGKDIFMTEEQKKYY------NAM1323
SCN5ALYMYIYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKLGGQDIFMTEEQKKYY------NAM1498
SCN7AIYMYCYFINFIIFGVFLPLSMLITVIIDNF>N<KHKIKLGGSNIFITVKQRKQY------RRL1221
SCN8AIYMYIYFVIFIIFGSFFTLNLFIGVIIDNF>N<QQKKKFGGQDIFMTEEQKKYY------NAM1492
SCN9ALYMYIYFVVFIIFGSFFTLNLFIGVIIDNF>N<QQKKKLGGQDIFMTEEQKKYY------NAM1474
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Q1170Rc.3509A>G Putative Benignrs200634867SIFT: tolerated
Polyphen: possibly damaging