No paralogue variants have been mapped to residue 1280 for CACNA1C.
| CACNA1C | AMNILNMLFTGLFTVEMILKLIAFKPKHYF>C<DAWNTFDALIVVGSIVDIAITEVNPAE--- | 1307 |
| CACNA1A | ALRVFNIVFTSLFSLECVLKVMAFGILNYF>R<DAWNIFDFVTVLGSITDILVTEFGNN---- | 1653 |
| CACNA1B | MLKCLNIVFTSMFSMECVLKIIAFGVLNYF>R<DAWNVFDFVTVLGSITDILVTEIAET---- | 1559 |
| CACNA1D | AMDILNMVFTGVFTVEMVLKVIAFKPKGYF>S<DAWNTFDSLIVIGSIIDVALSEADPTE--- | 1313 |
| CACNA1E | ALKYLNIAFTMVFSLECVLKVIAFGFLNYF>R<DTWNIFDFITVIGSITEIILTDSKLV---- | 1565 |
| CACNA1F | AMDILNMVFTGLFTIEMVLKIIAFKPKHYF>T<DAWNTFDALIVVGSIVDIAVTEVNNGG--- | 1278 |
| CACNA1G | ALKICNYIFTVIFVLESVFKLVAFGFRRFF>Q<DRWNQLDLAIVLLSIMGITLEEIEVN---- | 1698 |
| CACNA1H | ALKYCNYVFTIVFVFEAALKLVAFGFRRFF>K<DRWNQLDLAIVLLSLMGITLEEIEMS---- | 1704 |
| CACNA1I | ALKYCNYMFTTVFVLEAVLKLVAFGLRRFF>K<DRWNQLDLAIVLLSVMGITLEEIEIN---- | 1574 |
| CACNA1S | ISDILNVAFTIIFTLEMILKLMAFKARGYF>G<DPWNVFDFLIVIGSIIDVILSEIDTFLASS | 1209 |
| SCN10A | ILGKINQFFVAVFTGECVMKMFALR-QYYF>T<NGWNVFDFIVVVLSIASLIFSAILKS---- | 1562 |
| SCN11A | ILDHLNWVFVVIFTLECLIKIFALR-QYYF>T<NGWNLFDCVVVLLSIVSTMISTLENQ---- | 1452 |
| SCN1A | ILSRINLVFIVLFTGECVLKLISLR-HYYF>T<IGWNIFDFVVVILSIVGMFLAELIE----- | 1626 |
| SCN2A | ILYWINLVFIVLFTGECVLKLISLR-YYYF>T<IGWNIFDFVVVILSIVGMFLAELIE----- | 1616 |
| SCN3A | VLSRINLVFIVLFTGEFVLKLVSLR-HYYF>T<IGWNIFDFVVVILSIVGMFLAEMIE----- | 1611 |
| SCN4A | ILYNINMIFIIIFTGECVLKMLALR-QYYF>T<VGWNIFDFVVVILSIVGLALSDLIQ----- | 1438 |
| SCN5A | ILAKINLLFVAIFTGECIVKLAALR-HYYF>T<NSWNIFDFVVVILSIVGTVLSDIIQ----- | 1613 |
| SCN7A | ALYWINSIFVMLYTMECILKLIAFR-CFYF>T<IAWNIFDFMVVIFSITGLCLPMTVG----- | 1336 |
| SCN8A | ILYWINLVFVIFFTCECVLKMFALR-HYYF>T<IGWNIFDFVVVILSIVGMFLADIIE----- | 1607 |
| SCN9A | VLYWINVVFIILFTGECVLKLISLR-HYYF>T<VGWNIFDFVVVIISIVGMFLADLIE----- | 1589 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.C1280R | c.3838T>C | Putative Benign | SIFT: Polyphen: |