No paralogue variants have been mapped to residue 1446 for CACNA1C.
| CACNA1C | QDIMLACMPG--KKCAPESEP-SNSTEGET>P<--CGS-SFAVFYFISFYMLCAFLIINLFVA | 1473 |
| CACNA1A | HNIMLSCLSG--KPCDKNSGIL-----T-R>-<-ECGN-EFAYFYFVSFIFLCSFLMLNLFVA | 1808 |
| CACNA1B | HEIMLSCLSN--QACDE---Q------A-N>A<TECGS-DFAYFYFVSFIFLCSFLMLNLFVA | 1706 |
| CACNA1D | QEIMLACLPG--KLCDPESDY--NPGE-EY>T<--CGS-NFAIVYFISFYMLCAFLIINLFVA | 1481 |
| CACNA1E | QEIMLSCLGE--KGCEPDTTAPSGQNEN-E>-<-RCGT-DLAYVYFVSFIFFCSFLMLNLFVA | 1720 |
| CACNA1F | QEIMLASLPG--NRCDPESDF--GPGE-EF>T<--CGS-NFAIAYFISFFMLCAFLIINLFVA | 1438 |
| CACNA1G | NGIMKDTLRD----CDQEST-----C---->-<--YNT-VISPIYFVSFVLTAQFVLVNVVIA | 1848 |
| CACNA1H | NGIMKDTLRE----CSREDKH----C---L>S<--YLP-ALSPVYFVTFVLVAQFVLVNVVVA | 1857 |
| CACNA1I | NGIMKDTLRD----CTHDERS----C---L>S<--SLQ-FVSPLYFVSFVLTAQFVLINVVVA | 1727 |
| CACNA1S | QEILLACSYG--KLCDPESDY--APGE-EY>T<--CGT-NFAYYYFISFYMLCAFLVINLFVA | 1378 |
| SCN10A | DGLLSPILNTGPPYCDPNLPN-S-NGTRGD>-<--CGSPAVGIIFFTTYIIISFLIMVNMYIA | 1719 |
| SCN11A | DSLLSPMLRSKES-CN---------SSSEN>-<--CHLPGIATSYFVSYIIISFLIVVNMYIA | 1601 |
| SCN1A | DGLLAPILNSKPPDCDPNKVN-PGSSVKGD>-<--CGNPSVGIFFFVSYIIISFLVVVNMYIA | 1783 |
| SCN2A | DGLLAPILNSGPPDCDPDKDH-PGSSVKGD>-<--CGNPSVGIFFFVSYIIISFLVVVNMYIA | 1773 |
| SCN3A | DGLLAPILNSAPPDCDPDTIH-PGSSVKGD>-<--CGNPSVGIFFFVSYIIISFLVVVNMYIA | 1768 |
| SCN4A | DGLLNPILNSGPPDCDPNLEN-PGTSVKGD>-<--CGNPSIGICFFCSYIIISFLIVVNMYIA | 1595 |
| SCN5A | DGLLSPILNTGPPYCDPTLPN-S-NGSRGD>-<--CGSPAVGILFFTTYIIISFLIVVNMYIA | 1769 |
| SCN7A | DGMLDAIFNSKWSDCDPDKIN-PGTQVRGD>-<--CGNPSVGIFYFVSYILISWLIIVNMYIV | 1493 |
| SCN8A | DGLLLPILN-RPPDCSLDKEH-PGSGFKGD>-<--CGNPSVGIFFFVSYIIISFLIVVNMYIA | 1763 |
| SCN9A | DGLLAPILNSKPPDCDPKKVH-PGSSVEGD>-<--CGNPSVGIFYFVSYIIISFLVVVNMYIA | 1746 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.P1446A | c.4336C>G | Putative Benign | SIFT: Polyphen: |