No paralogue variants have been mapped to residue 1457 for CACNA1C.
| CACNA1C | CAPESEP-SNSTEGETP--CGS-SFAVFYF>I<SFYMLCAFLIINLFVAVIMDNFDYLTRDWS | 1487 |
| CACNA1A | CDKNSGIL-----T-R--ECGN-EFAYFYF>V<SFIFLCSFLMLNLFVAVIMDNFEYLTRDSS | 1822 |
| CACNA1B | CDE---Q------A-NATECGS-DFAYFYF>V<SFIFLCSFLMLNLFVAVIMDNFEYLTRDSS | 1720 |
| CACNA1D | CDPESDY--NPGE-EYT--CGS-NFAIVYF>I<SFYMLCAFLIINLFVAVIMDNFDYLTRDWS | 1495 |
| CACNA1E | CEPDTTAPSGQNEN-E--RCGT-DLAYVYF>V<SFIFFCSFLMLNLFVAVIMDNFEYLTRDSS | 1734 |
| CACNA1F | CDPESDF--GPGE-EFT--CGS-NFAIAYF>I<SFFMLCAFLIINLFVAVIMDNFDYLTRDWS | 1452 |
| CACNA1G | CDQEST-----C-------YNT-VISPIYF>V<SFVLTAQFVLVNVVIAVLMKHLEESNKEAK | 1862 |
| CACNA1H | CSREDKH----C---LS--YLP-ALSPVYF>V<TFVLVAQFVLVNVVVAVLMKHLEESNKEAR | 1871 |
| CACNA1I | CTHDERS----C---LS--SLQ-FVSPLYF>V<SFVLTAQFVLINVVVAVLMKHLDDSNKEAQ | 1741 |
| CACNA1S | CDPESDY--APGE-EYT--CGT-NFAYYYF>I<SFYMLCAFLVINLFVAVIMDNFDYLTRDWS | 1392 |
| SCN10A | CDPNLPN-S-NGTRGD---CGSPAVGIIFF>T<TYIIISFLIMVNMYIAVILENFNVATEEST | 1733 |
| SCN11A | CN---------SSSEN---CHLPGIATSYF>V<SYIIISFLIVVNMYIAVILENFNTATEESE | 1615 |
| SCN1A | CDPNKVN-PGSSVKGD---CGNPSVGIFFF>V<SYIIISFLVVVNMYIAVILENFSVATEESA | 1797 |
| SCN2A | CDPDKDH-PGSSVKGD---CGNPSVGIFFF>V<SYIIISFLVVVNMYIAVILENFSVATEESA | 1787 |
| SCN3A | CDPDTIH-PGSSVKGD---CGNPSVGIFFF>V<SYIIISFLVVVNMYIAVILENFSVATEESA | 1782 |
| SCN4A | CDPNLEN-PGTSVKGD---CGNPSIGICFF>C<SYIIISFLIVVNMYIAIILENFNVATEESS | 1609 |
| SCN5A | CDPTLPN-S-NGSRGD---CGSPAVGILFF>T<TYIIISFLIVVNMYIAIILENFSVATEEST | 1783 |
| SCN7A | CDPDKIN-PGTQVRGD---CGNPSVGIFYF>V<SYILISWLIIVNMYIVVVMEFLNIASKKKN | 1507 |
| SCN8A | CSLDKEH-PGSGFKGD---CGNPSVGIFFF>V<SYIIISFLIVVNMYIAIILENFSVATEESA | 1777 |
| SCN9A | CDPKKVH-PGSSVEGD---CGNPSVGIFYF>V<SYIIISFLVVVNMYIAVILENFSVATEEST | 1760 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.I1457V | c.4369A>G | Putative Benign | SIFT: Polyphen: |