No paralogue variants have been mapped to residue 1545 for CACNA1C.
| CACNA1C | VVTLLRRIQPPLG--FGKLCPHRVACKRLV>S<MNMPLNSDG-TVMFNATLFALVRTALRIKT | 1574 |
| CACNA1A | MYSLLRVISPPLG--LGKKCPHRVACKRLL>R<MDLPVADD-NTVHFNSTLMALIRTALDIKI | 1909 |
| CACNA1B | MFEMLKHMSPPLG--LGKKCPARVAYKRLV>R<MNMPISNEDMTVHFTSTLMALIRTALEIKL | 1808 |
| CACNA1D | VVTLLRRIQPPLG--FGKLCPHRVACKRLV>A<MNMPLNSDG-TVMFNATLFALVRTALKIKT | 1582 |
| CACNA1E | MYEMLTLMSPPLG--LGKRCPSKVAYKRLV>L<MNMPVAED-MTVHFTSTLMALIRTALDIKI | 1821 |
| CACNA1F | VVALLRRIQPPLG--FGKLCPHRVACKRLV>A<MNMPLNSDG-TVTFNATLFALVRTSLKIKT | 1539 |
| CACNA1G | PF-LWPGVEGPDS--PDSPKPGAL------>-<--HPAAHA-RSASHFSLEHPTDRQLFDTI- | 1935 |
| CACNA1H | P---------PLP--QESPG--AR------>-<-DAPN---------------LVARKV---- | 1919 |
| CACNA1I | PGAPGR---GPGGAGGGGDT--EG---GLC>R<RCYSPAQE-N--LWLDSVSLIIKDSL---- | 1814 |
| CACNA1S | VVTLLRRIQPPLG--FGKFCPHRVACKRLV>G<MNMPLNSDG-TVTFNATLFALVRTALKIKT | 1479 |
| SCN10A | LSDFADTLSGPLR--IPK--PNRN---ILI>Q<MDLPLVPGD-KIHCLDILFAFTKNVLGES- | 1815 |
| SCN11A | LSDFADALPEPLR--VAK--PNKY---QFL>V<MDLPMVSED-RLHCMDILFAFTARVLGGS- | 1697 |
| SCN1A | LSQFAAALEPPLN--LPQ--PNKL---QLI>A<MDLPMVSGD-RIHCLDILFAFTKRVLGES- | 1879 |
| SCN2A | LSDFADALDPPLL--IAK--PNKV---QLI>A<MDLPMVSGD-RIHCLDILFAFTKRVLGES- | 1869 |
| SCN3A | LSDFAAALDPPLL--IAK--PNKV---QLI>A<MDLPMVSGD-RIHCLDILFAFTKRVLGES- | 1864 |
| SCN4A | LSDFVDTLQEPLR--IAK--PNKI---KLI>T<LDLPMVPGD-KIHCLDILFALTKEVLGDS- | 1691 |
| SCN5A | LSDFADALSEPLR--IAK--PNQI---SLI>N<MDLPMVSGD-RIHCMDILFAFTKRVLGES- | 1865 |
| SCN7A | LSDFAAALDPPLF--MAK--PNKG---QLI>A<LDLPMAVGD-RIHCLDILLAFTKRVMGQD- | 1589 |
| SCN8A | LADFADALEHPLR--VPK--PNTI---ELI>A<MDLPMVSGD-RIHCLDILFAFTKRVLGDS- | 1859 |
| SCN9A | LSDFAAALDPPLL--IAK--PNKV---QLI>A<MDLPMVSGD-RIHCLDILFAFTKRVLGES- | 1842 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.S1545P | c.4633T>C | Putative Benign | rs1057774 | SIFT: deleterious Polyphen: |