No paralogue variants have been mapped to residue 1742 for CACNA1C.
| CACNA1C | T---T-------QRPLHINKAGSS-QGDTE>S<PSHEKLVDSTFTPSSY-------SSTGSNA | 1765 |
| CACNA1A | A----------------------------->-<------------------------------ | 2099 |
| CACNA1B | A----------------------------->-<------------------------------ | 2008 |
| CACNA1D | T---T-------HRPLHVQRPSIPPASDTE>K<PLFPPAGNSVCHNHHNHNSIGKQVPTSTNA | 1776 |
| CACNA1E | V----------------------------->-<------------------------------ | 2006 |
| CACNA1F | VGDRL-------PDSLSFG---P------->-<--SDDDRG---------------TPTSSQP | 1708 |
| CACNA1G | -----------ADT-----------SYILQ>L<PKDAPHLLQPHS-APT--------WGTIPK | 2116 |
| CACNA1H | P---AAP----GGE-----------EAEAS>D<PADEEVSHITSS-ACP--------WQPTAE | 2116 |
| CACNA1I | S---WASLRSPRVN-----------CTLLR>Q<ATGSDTSLDASP-SSS--------AGSL-Q | 2029 |
| CACNA1S | A---N-------QRPLQFAEIE---MEEME>S<PVFLE---D-FPQDPR-------TNPLARA | 1659 |
| SCN10A | ------------------------------>-<----ETASATSF-P----------PSYESV | 1924 |
| SCN11A | ------------------------------>-<----L--------------------CNGDL | 1778 |
| SCN1A | ------------------------------>-<----DLTMSTAACP----------PSYDRV | 1989 |
| SCN2A | ------------------------------>-<----DMTPSTTS-P----------PSYDSV | 1978 |
| SCN3A | ------------------------------>-<----DGSSSTTS-P----------PSYDSV | 1973 |
| SCN4A | ------------------------------>-<----EKGEAGDA-G----------PTMGLM | 1808 |
| SCN5A | ------------------------------>-<----SSISSTSF-P----------PSYDSV | 1980 |
| SCN7A | ------------------------------>-<------------------------------ | |
| SCN8A | ------------------------------>-<----ESTPSTAS-L----------PSYDSV | 1950 |
| SCN9A | ------------------------------>-<----DATSSTTS-P----------PSYDSV | 1950 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.S1742L | c.5225C>T | Putative Benign | rs375571032 | SIFT: tolerated Polyphen: benign |