No paralogue variants have been mapped to residue 1774 for CACNA1C.
| CACNA1C | FTPSSY-------SSTGSNANI--NNANNT>A<LGRLPRPAG----YPSTVSTVEGHGPPLSP | 1800 |
| CACNA1A | -----------------------------E>N<QRRRGRPR----------GNNLSTISDTSP | 2121 |
| CACNA1B | -----------------------------E>T<Q-----P-----------------VTDASP | 2018 |
| CACNA1D | CHNHHNHNSIGKQVPTSTNANL--NNANMS>K<AAHGKRPSIGNLEHVSENGHHSSHKHDREP | 1815 |
| CACNA1E | -----------------------------D>P<Q----------------------VVTDPSS | 2016 |
| CACNA1F | -------------TPTSSQPSV--PQAGSN>T<HRRGSG------------------------ | 1723 |
| CACNA1G | HS-APT--------WGTIPKLPPPG---RS>P<L------------------AQRPLRRQAAI | 2136 |
| CACNA1H | SS-ACP--------WQPTAEPH-------->-<------------------------------ | 2118 |
| CACNA1I | SP-SSS--------AGSL-QTTLED---SL>T<----------------------------LS | 2039 |
| CACNA1S | FPQDPR-------TNPLARANT--NNAN-->-<------------------------------ | 1665 |
| SCN10A | SF-P----------PSYESVT--------->-<------------------------------ | 1925 |
| SCN11A | ---------------CNGDLS--------->-<------------------------------ | 1779 |
| SCN1A | AACP----------PSYDRVT--------->-<------------------------------ | 1990 |
| SCN2A | TS-P----------PSYDSVT--------->-<------------------------------ | 1979 |
| SCN3A | TS-P----------PSYDSVT--------->-<------------------------------ | 1974 |
| SCN4A | DA-G----------PTMGLMP--------->-<------------------------------ | 1809 |
| SCN5A | SF-P----------PSYDSVT--------->-<------------------------------ | 1981 |
| SCN7A | ------------------------------>-<------------------------------ | |
| SCN8A | AS-L----------PSYDSVT--------->-<------------------------------ | 1951 |
| SCN9A | TS-P----------PSYDSVT--------->-<------------------------------ | 1951 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A1774T | c.5320G>A | Putative Benign | SIFT: Polyphen: |