Paralogue Annotation for CACNA1C residue 1787

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1787
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1787

No paralogue variants have been mapped to residue 1787 for CACNA1C.



CACNA1CSNANI--NNANNTALGRLPRPAG----YPS>T<VSTVEGHGPPLSPAIR--VQEVAWKLSSNR1815
CACNA1A------------ENQRRRGRPR-------->-<-GNNLSTISDTSPMKRSASVL-------G-2130
CACNA1B------------ETQ-----P--------->-<-------VTDASPMKRSISTL-------AQ2028
CACNA1DTNANL--NNANMSKAAHGKRPSIGNLEHVS>E<NGHHSSHKHDREPQRRSSVKRTRYYETYIR1832
CACNA1E------------DPQ--------------->-<------VVTDPSSMRRSFSTI-------RD2026
CACNA1FSQPSV--PQAGSNTHRRGSG---------->-<-----------------------ALIFTIP1730
CACNA1GIPKLPPPG---RSPL--------------->-<--AQRPLRRQAAIRTDSLDVQ-------GL2146
CACNA1HTAEPH------------------------->-<------------------------------2118
CACNA1IL-QTTLED---SLT---------------->-<-----------LSDSP--------------2042
CACNA1SARANT--NNAN------------------->-<------------------------------1665
SCN10AESVT-------------------------->-<------------------------------1925
SCN11AGDLS-------------------------->-<------------------------------1779
SCN1ADRVT-------------------------->-<------------------------------1990
SCN2ADSVT-------------------------->-<------------------------------1979
SCN3ADSVT-------------------------->-<------------------------------1974
SCN4AGLMP-------------------------->-<------------------------------1809
SCN5ADSVT-------------------------->-<------------------------------1981
SCN7A------------------------------>-<------------------------------
SCN8ADSVT-------------------------->-<------------------------------1951
SCN9ADSVT-------------------------->-<------------------------------1951
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1787Mc.5360C>T Benignrs192749597SIFT: tolerated
Polyphen: possibly damaging