Paralogue Annotation for CACNA1C residue 1792

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1792
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1792

No paralogue variants have been mapped to residue 1792 for CACNA1C.



CACNA1C--NNANNTALGRLPRPAG----YPSTVSTV>E<GHGPPLSPAIR--VQEVAWKLSSNRCHSRE1820
CACNA1A-------ENQRRRGRPR----------GNN>L<STISDTSPMKRSASVL-------G---PKA2133
CACNA1B-------ETQ-----P-------------->-<--VTDASPMKRSISTL-------AQ-RPRG2032
CACNA1D--NNANMSKAAHGKRPSIGNLEHVSENGHH>S<SHKHDREPQRRSSVKRTRYYETYIRSDSGD1837
CACNA1E-------DPQ-------------------->-<-VVTDPSSMRRSFSTI-------RDKRSN-2030
CACNA1F--PQAGSNTHRRGSG--------------->-<------------------ALIFTIPEEGNS1735
CACNA1GPPG---RSPL------------------AQ>R<PLRRQAAIRTDSLDVQ-------GL-GSRE2150
CACNA1H------------------------------>-<------------------------------
CACNA1ILED---SLT--------------------->-<------LSDSP-------------------2042
CACNA1S--NNAN------------------------>-<------------------------------1665
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1792Gc.5375A>G Putative Benignrs374177870SIFT: tolerated
Polyphen: benign
p.E1792Kc.5374G>A Putative BenignSIFT: tolerated
Polyphen: benign