Paralogue Annotation for CACNA1C residue 1840

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1840
Reference Amino Acid: K - Lysine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1840

No paralogue variants have been mapped to residue 1840 for CACNA1C.



CACNA1CQAAMAGQEET------------SQDETYEV>K<MNHDTEACSEPSLLSTE------MLSYQDD1864
CACNA1ARLDDYSLERV---------------PPEEN>Q<RHHQ--R---RRDRSHRASERSLGRYTDV-2174
CACNA1BHLCSTTPDRP---------------PPSQA>S<SHHHHHRCHRRRDRKQRSLEKGPSLSADM-2078
CACNA1DQLPTICREDPEIHGYFRDPHCLGEQEYFSS>E<ECYEDDSSPTWSRQNYGYYSRYPGRNIDSE1899
CACNA1E---SSWLEEF---------------SMERS>S<ENTY--K---SRRRSYHSSLRLSAHRLNS-2067
CACNA1FPKGTKGQNKQ------------DEDEEVPD>R<LSYLDEQAGTPP-CSVL-------------1771
CACNA1GLLAEVSGPSP------------PLARAYSF>W<GQSS--T---Q-------------------2176
CACNA1H------------------------------>-<------------------------------
CACNA1I------------------------------>-<------------------------------
CACNA1S-----------------------------A>N<VAYGNSNHSNSHVFSSVHYEREFPEETET-1696
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.K1840Ec.5518A>G Putative Benignrs199601269SIFT: tolerated
Polyphen: benign