Paralogue Annotation for CACNA1C residue 1845

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1845
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 1845

No paralogue variants have been mapped to residue 1845 for CACNA1C.

CACNA1C	GQEET------------SQDETYEVKMNHD>T<EACSEPSLLSTE------MLSYQDDENRQL	1869
CACNA1A	SLERV---------------PPEENQRHHQ>-<-R---RRDRSHRASERSLGRYTDV---DTG	2177
CACNA1B	TPDRP---------------PPSQASSHHH>H<HRCHRRRDRKQRSLEKGPSLSADM---DGA	2081
CACNA1D	CREDPEIHGYFRDPHCLGEQEYFSSEECYE>D<DSSPTWSRQNYGYYSRYPGRNIDSERPRGY	1904
CACNA1E	WLEEF---------------SMERSSENTY>-<-K---SRRRSYHSSLRLSAHRLNS---DSG	2070
CACNA1F	GQNKQ------------DEDEEVPDRLSYL>D<EQAGTPP-CSVL----------------LP	1773
CACNA1G	SGPSP------------PLARAYSFWGQSS>-<-T---Q---------------------AQQ	2179
CACNA1H	------------------------------>-<------------------------------
CACNA1I	------------------------------>-<------------------------------
CACNA1S	------------------------ANVAYG>N<SNHSNSHVFSSVHYEREFPEETET------	1696
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T1845M	c.5534C>T	Putative Benign			SIFT: Polyphen: