Paralogue Annotation for CACNA1C residue 1850

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1850
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1850

No paralogue variants have been mapped to residue 1850 for CACNA1C.



CACNA1C------------SQDETYEVKMNHDTEACS>E<PSLLSTE------MLSYQDDENRQL-----1869
CACNA1A---------------PPEENQRHHQ--R-->-<RRDRSHRASERSLGRYTDV---DTGL----2178
CACNA1B---------------PPSQASSHHHHHRCH>R<RRDRKQRSLEKGPSLSADM---DGAP----2082
CACNA1DEIHGYFRDPHCLGEQEYFSSEECYEDDSSP>T<WSRQNYGYYSRYPGRNIDSERPRGYHHPQG1909
CACNA1E---------------SMERSSENTY--K-->-<SRRRSYHSSLRLSAHRLNS---DSGH----2071
CACNA1F------------DEDEEVPDRLSYLDEQAG>T<PP-CSVL----------------LP-----1773
CACNA1G------------PLARAYSFWGQSS--T-->-<Q---------------------AQQ-----2179
CACNA1H------------------------------>-<------------------------------
CACNA1I------------------------------>-<------------------------------
CACNA1S-------------------ANVAYGNSNHS>N<SHVFSSVHYEREFPEETET-----------1696
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1850Ac.5549A>C Putative Benignrs375846068SIFT: tolerated
Polyphen: benign