Paralogue Annotation for CACNA1C residue 1863

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1863
Reference Amino Acid: D - Aspartate
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 1863

No paralogue variants have been mapped to residue 1863 for CACNA1C.

CACNA1C	VKMNHDTEACSEPSLLSTE------MLSYQ>D<DENRQL--------TLPEEDKRDIRQSPKR	1885
CACNA1A	NQRHHQ--R---RRDRSHRASERSLGRYTD>V<---DTGL---------------GTDLSMTT	2186
CACNA1B	ASSHHHHHRCHRRRDRKQRSLEKGPSLSAD>M<---DGAP---------------SSAVGPGL	2090
CACNA1D	SEECYEDDSSPTWSRQNYGYYSRYPGRNID>S<ERPRGYHHPQGFLEDDDSPVCYDSRRSPRR	1928
CACNA1E	SSENTY--K---SRRRSYHSSLRLSAHRLN>S<---DSGH---------------KSDT----	2075
CACNA1F	DRLSYLDEQAGTPP-CSVL----------->-<----LP--------PHRAQRYMDGHLVPRR	1789
CACNA1G	FWGQSS--T---Q----------------->-<---AQQ--------HSR------SHSKISK	2189
CACNA1H	------------------------------>-<------------------------------
CACNA1I	------------------------------>-<----------------------------RR	2044
CACNA1S	ANVAYGNSNHSNSHVFSSVHYEREFPEETE>T<------------------------PATRGR	1702
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D1863N	c.5587G>A	Putative Benign			SIFT: Polyphen: