Paralogue Annotation for CACNA1C residue 1865

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1865
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1865

No paralogue variants have been mapped to residue 1865 for CACNA1C.



CACNA1CMNHDTEACSEPSLLSTE------MLSYQDD>E<NRQL--------TLPEEDKRDIRQSPKRGF1887
CACNA1ARHHQ--R---RRDRSHRASERSLGRYTDV->-<-DTGL---------------GTDLSMTTQS2188
CACNA1BSHHHHHRCHRRRDRKQRSLEKGPSLSADM->-<-DGAP---------------SSAVGPGLPP2092
CACNA1DECYEDDSSPTWSRQNYGYYSRYPGRNIDSE>R<PRGYHHPQGFLEDDDSPVCYDSRRSPRRRL1930
CACNA1EENTY--K---SRRRSYHSSLRLSAHRLNS->-<-DSGH---------------KSDT------2075
CACNA1FLSYLDEQAGTPP-CSVL------------->-<--LP--------PHRAQRYMDGHLVPRRRL1791
CACNA1GGQSS--T---Q------------------->-<-AQQ--------HSR------SHSKISKHM2191
CACNA1H------------------------------>-<------------------------------
CACNA1I------------------------------>-<--------------------------RRAL2046
CACNA1SVAYGNSNHSNSHVFSSVHYEREFPEETET->-<----------------------PATRGRAL1704
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1865Kc.5593G>A Benignrs200231105, rs71458011SIFT: tolerated
Polyphen: