Paralogue Annotation for CACNA1C residue 1867

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1867
Reference Amino Acid: R - Arginine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1867

No paralogue variants have been mapped to residue 1867 for CACNA1C.



CACNA1CHDTEACSEPSLLSTE------MLSYQDDEN>R<QL--------TLPEEDKRDIRQSPKRGFLR1889
CACNA1AHQ--R---RRDRSHRASERSLGRYTDV--->D<TGL---------------GTDLSMTTQSGD2190
CACNA1BHHHHRCHRRRDRKQRSLEKGPSLSADM--->D<GAP---------------SSAVGPGLPPGE2094
CACNA1DYEDDSSPTWSRQNYGYYSRYPGRNIDSERP>R<GYHHPQGFLEDDDSPVCYDSRRSPRRRLLP1932
CACNA1ETY--K---SRRRSYHSSLRLSAHRLNS--->D<SGH---------------KSDT--------2075
CACNA1FYLDEQAGTPP-CSVL--------------->-<LP--------PHRAQRYMDGHLVPRRRLLP1793
CACNA1GSS--T---Q--------------------->A<QQ--------HSR------SHSKISKHMTP2193
CACNA1H------------------------------>-<------------------------------
CACNA1I------------------------------>-<------------------------RRALGP2048
CACNA1SYGNSNHSNSHVFSSVHYEREFPEETET--->-<--------------------PATRGRALGQ1706
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R1867Wc.5599C>T Putative Benignrs369421219SIFT: deleterious
Polyphen: probably damaging
p.R1867Qc.5600G>A Putative BenignSIFT: tolerated
Polyphen: benign