No paralogue variants have been mapped to residue 1945 for CACNA1C.
| CACNA1C | ALAVAGLSP--LL------------QRSHS>P<ASFPRPFATPPATPGSRGWPPQPVPTLRLE | 1975 |
| CACNA1A | HRQHH--------------HHHHHHHHPPP>P<DKDRYAQ-ERPDHG------RARARDQRWS | 2247 |
| CACNA1B | TSPTAGQEPGPHPQGSGSVNGSPLLSTSGA>S<TPGRGGRRQLPQTP------LTPRPSITYK | 2205 |
| CACNA1D | IMAVAGLDS--SK------------AQKYS>P<SHSTRSWATPPATPPYRDWTPCYTPLIQVE | 2024 |
| CACNA1E | RSPSEGRSQTPNRQGTGSLSESSIPSVSDT>S<TP-RRSRRQLPPVP------PKPRPLLSYS | 2173 |
| CACNA1F | -----------HR------------GRNSG>P<NRAQGSWATPPQRG-----RLLYAPLLLVE | 1856 |
| CACNA1G | --L--------------------------->-<-----SWISGDLLPPGGQEEPPSPRDLKKC | 2246 |
| CACNA1H | ------------------------------>-<------------------------RDLRRL | 2135 |
| CACNA1I | ------------------------------>-<------------------------PAARRR | 2066 |
| CACNA1S | -LLTQRAMP--RG------------QAPPA>P<CQCP-----------------------RVE | 1747 |
| SCN10A | ------------------------------>-<---------------------S---S--SI | 1940 |
| SCN11A | ------------------------------>-<-------------------------G--KV | 1788 |
| SCN1A | ------------------------------>-<---------------------Q---E--GK | 2002 |
| SCN2A | ------------------------------>-<---------------------K---D--KS | 1991 |
| SCN3A | ------------------------------>-<---------------------K---D--KP | 1986 |
| SCN4A | ------------------------------>-<---------------------P---A--PP | 1822 |
| SCN5A | ------------------------------>-<---------------------S---D--YS | 1996 |
| SCN7A | ------------------------------>-<-------------------------S--P- | 1677 |
| SCN8A | ------------------------------>-<---------------------E---G--RR | 1966 |
| SCN9A | ------------------------------>-<---------------------Q---D--RT | 1963 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.P1945S | c.5833C>T | Putative Benign | SIFT: tolerated Polyphen: benign |