Paralogue Annotation for CACNA1C residue 2011

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2011
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 2011

No paralogue variants have been mapped to residue 2011 for CACNA1C.



CACNA1CEKLNSSFPSIHCGSWAETTPGGGGSSAARR>V<RPVSLMVPSQA---GAPGRQFHGSASSLVE2038
CACNA1A------------------------------>-<------------------------------
CACNA1B---S--PIHFA------------------->-<GAQTSLPAFSP---GRLSRGLSEHNA----2238
CACNA1DDQVNGSLPSLHRSSWYTDEP----DISYRT>F<TPASLTVPSSF---RNKNSDKQRSADSLVE2083
CACNA1E---H--AGSIS------------------->-<PPADGSEEGSP---LT-SQALESNNACLTE2209
CACNA1FEGYLGRS-----------------SGPLRT>F<T--CLHVPGTH---SDPSHGKRGSADSLVE1900
CACNA1GQSCQRRPTSWLDEQRRHSIAVSCLDSGSQP>H<LGTDPSNLGG---QPLGGPGSRPKKKLSPP2309
CACNA1HQGFLDKPGR-ADEQWRPSAELGSGEP---->-<--GEAKAWGP---EAEPALGARRKKKMSPP2190
CACNA1IRGLFSLRG--LRAHQRSHSSGGSTSPGCTH>H<DSMDPSDEEGRGGAGGGGAGSEHSETLSSL2130
CACNA1SDRKSSTPGSLHE-----ETP---------->-<-----HSRSTR---ENTSRCSAPATALLIQ1789
SCN10A------E----------------------->-<--------------------------A---1946
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------L----------------------->-<--------------------------A---2002
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V2011Ic.6031G>A Putative Benignrs193922615SIFT: tolerated
Polyphen: benign
p.V2011Fc.6031G>T Putative BenignSIFT:
Polyphen:
p.V2011Ac.6032T>C Putative BenignSIFT:
Polyphen: