Paralogue Annotation for CACNA1C residue 2054

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2054
Reference Amino Acid: K - Lysine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 2054

No paralogue variants have been mapped to residue 2054 for CACNA1C.



CACNA1C-----------------------------P>K<FIEVTT-QELADACDMTIEEMESAADNILS2083
CACNA1A------------------------------>-<------------------------------
CACNA1B-----------------------------S>D<PYLGQR-LDSEASVHALPEDTLTFEEAVAT2287
CACNA1D-----------------------------P>K<FVSATK-HEIADACDLTIDEMESAASTLLN2128
CACNA1E-----------------------------S>E<PYLALH-EDSHAS-DCGEEETLTFEAAVAT2258
CACNA1F-----------------------------P>R<FVALAK-QEIADACRLTLDEMDNAASDLLA1945
CACNA1G-----------------------------P>P<SPGICLRRRAPSSDSKDPLASGPPDSMAAS2355
CACNA1HATPHRDSLEPTEGSGAGGDPAAKGERWGQA>S<CRAEHLTVPSFAFEPLDLGVPSGDPFLDGS2285
CACNA1I-----------------------------P>P<APGLTPARKFSSTSSLAAPGRPHAAALAHG2173
CACNA1S-----------------------------A>N<FIMATG-QALADACQMEPEEVEIMATELLK1834
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<------------------------------
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.K2054Rc.6161A>G Putative Benignrs200588235SIFT: tolerated
Polyphen: benign