Paralogue Annotation for CACNA1C residue 2077

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2077
Reference Amino Acid: A - Alanine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 2077

No paralogue variants have been mapped to residue 2077 for CACNA1C.

CACNA1C	-----PKFIEVTT-QELADACDMTIEEMES>A<ADNILSGGAPQSPNGALLPFVNCRDAG---	2104
CACNA1A	------------------------------>-<------------------------------
CACNA1B	-----SDPYLGQR-LDSEASVHALPEDTLT>F<EEAVATNSGRSSRTSYVSSLTSQSHPL---	2308
CACNA1D	-----PKFVSATK-HEIADACDLTIDEMES>A<ASTLLNGNVRPRANGDVGPLSHRQDYE---	2149
CACNA1E	-----SEPYLALH-EDSHAS-DCGEEETLT>F<EAAVATSLGRSNTIGSAPPLRHSW------	2276
CACNA1F	-----PRFVALAK-QEIADACRLTLDEMDN>A<ASDLLAQGTSS-------------------	1950
CACNA1G	-----PPSPGICLRRRAPSSDSKDPLASGP>P<DSMAASPSPKKDVLSLSGLSSDPADLD---	2376
CACNA1H	ERWGQASCRAEHLTVPSFAFEPLDLGVPSG>D<PFLDGSHSVTPESRASSSGAIVPLEPPESE	2309
CACNA1I	-----PPAPGLTPARKFSSTSSLAAPGRPH>A<AALAHGLARSPSWAADRSKDPPGRAPLPMG	2197
CACNA1S	-----ANFIMATG-QALADACQMEPEEVEI>M<ATELLKGREAPEGMASSLGCLNL-------	1851
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A2077T	c.6229G>A	Putative Benign			SIFT: Polyphen: