Paralogue Annotation for CACNA1C residue 2080

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2080
Reference Amino Acid: N - Asparagine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 2080

No paralogue variants have been mapped to residue 2080 for CACNA1C.

CACNA1C	--PKFIEVTT-QELADACDMTIEEMESAAD>N<ILSGGAPQSPNGALLPFVNCRDAG---QDR	2107
CACNA1A	------------------------------>-<------------------------------
CACNA1B	--SDPYLGQR-LDSEASVHALPEDTLTFEE>A<VATNSGRSSRTSYVSSLTSQSHPL---RRV	2311
CACNA1D	--PKFVSATK-HEIADACDLTIDEMESAAS>T<LLNGNVRPRANGDVGPLSHRQDYE---LQD	2152
CACNA1E	--SEPYLALH-EDSHAS-DCGEEETLTFEA>A<VATSLGRSNTIGSAPPLRHSW-------QM	2278
CACNA1F	--PRFVALAK-QEIADACRLTLDEMDNAAS>D<LLAQGTSS----------------------	1950
CACNA1G	--PPSPGICLRRRAPSSDSKDPLASGPPDS>M<AASPSPKKDVLSLSGLSSDPADLD------	2376
CACNA1H	GQASCRAEHLTVPSFAFEPLDLGVPSGDPF>L<DGSHSVTPESRASSSGAIVPLEPPESEPPM	2312
CACNA1I	--PPAPGLTPARKFSSTSSLAAPGRPHAAA>L<AHGLARSPSWAADRSKDPPGRAPLPMGLGP	2200
CACNA1S	--ANFIMATG-QALADACQMEPEEVEIMAT>E<LLKGREAPEGMASSLGCLNL----------	1851
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.Asn2080Ser	c.6239A>G	Unknown			SIFT: Polyphen: