Paralogue Annotation for CACNA1C residue 2085

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2085
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 2085

No paralogue variants have been mapped to residue 2085 for CACNA1C.

CACNA1C	IEVTT-QELADACDMTIEEMESAADNILSG>G<APQSPNGALLPFVNCRDAG---QDRAGGEE	2112
CACNA1A	------------------------------>-<------------------------------
CACNA1B	YLGQR-LDSEASVHALPEDTLTFEEAVATN>S<GRSSRTSYVSSLTSQSHPL---RRVPNGYH	2316
CACNA1D	VSATK-HEIADACDLTIDEMESAASTLLNG>N<VRPRANGDVGPLSHRQDYE---LQDFGPGY	2157
CACNA1E	YLALH-EDSHAS-DCGEEETLTFEAAVATS>L<GRSNTIGSAPPLRHSW-------QMPNGHY	2283
CACNA1F	VALAK-QEIADACRLTLDEMDNAASDLLAQ>G<TSS-------------------------LY	1952
CACNA1G	PGICLRRRAPSSDSKDPLASGPPDSMAASP>S<PKKDVLSLSGLSSDPADLD-----------	2376
CACNA1H	RAEHLTVPSFAFEPLDLGVPSGDPFLDGSH>S<VTPESRASSSGAIVPLEPPESEPPMPVGDP	2317
CACNA1I	PGLTPARKFSSTSSLAAPGRPHAAALAHGL>A<RSPSWAADRSKDPPGRAPLPMGLGPLAPP-	2204
CACNA1S	IMATG-QALADACQMEPEEVEIMATELLKG>R<EAPEGMASSLGCLNL---------------	1851
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G2085D	c.6254G>A	Putative Benign			SIFT: Polyphen: