Paralogue Annotation for CACNA1C residue 2110

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2110
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 2110

No paralogue variants have been mapped to residue 2110 for CACNA1C.

CACNA1C	SGGAPQSPNGALLPFVNCRDAG---QDRAG>G<EEDA----------GCV-----RARGRPSE	2125
CACNA1A	------------------------------>-<-----------------------------R	2248
CACNA1B	TNSGRSSRTSYVSSLTSQSHPL---RRVPN>G<YHCTLG-LS--------------SGGR--A	2327
CACNA1D	NGNVRPRANGDVGPLSHRQDYE---LQDFG>P<GYSD----------E-E-----PDPGR-DE	2168
CACNA1E	TSLGRSNTIGSAPPLRHSW-------QMPN>G<HYRRRR-RG-----GPG-----PGMMCGAV	2300
CACNA1F	AQGTSS------------------------>-<LYSD----------E-E-----SILSRFDE	1964
CACNA1G	SPSPKKDVLSLSGLSSDPADLD-------->-<------------------------------	2376
CACNA1H	SHSVTPESRASSSGAIVPLEPPESEPPMPV>G<DPPEKRRGLYLTVPQ-CPLEKPGSPSA--T	2342
CACNA1I	GLARSPSWAADRSKDPPGRAPLPMGLGPLA>P<P--------------------PQPLPG--E	2211
CACNA1S	KGREAPEGMASSLGCLNL------------>-<----------------G-----SSLGSLDQ	1860
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<-----------------------------D	2003
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G2110S	c.6328G>A	Putative Benign			SIFT: Polyphen: