No paralogue variants have been mapped to residue 2118 for CACNA1C.
| CACNA1C | --QDRAGGEEDA----------GCV----->R<ARGRPSEEELQDSRVYVSSL | 2138 |
| CACNA1A | ------------------------------>-<------RSPSEGREHMAHRQ | 2261 |
| CACNA1B | --RRVPNGYHCTLG-LS------------->-<SGGR--ARHSYHHPDQDHWC | 2340 |
| CACNA1D | --LQDFGPGYSD----------E-E----->P<DPGR-DEEDLADEMICITTL | 2181 |
| CACNA1E | ---QMPNGHYRRRR-RG-----GPG----->P<GMMCGAVNNLLSDTEEDDKC | 2313 |
| CACNA1F | --------LYSD----------E-E----->S<ILSRFDEEDLGDEMACVHAL | 1977 |
| CACNA1G | ------------------------------>-<-------------------P | 2377 |
| CACNA1H | SEPPMPVGDPPEKRRGLYLTVPQ-CPLEKP>G<SPSA--TPA-PG-GGADDPV | 2353 |
| CACNA1I | MGLGPLAPP--------------------P>Q<PLPG--ELE-PGDAASKRKR | 2223 |
| CACNA1S | ------------------------G----->S<SLGSLDQHQGSQETLIPPRL | 1873 |
| SCN10A | ------------------------------>-<----------TSMELIAPGP | 1956 |
| SCN11A | ------------------------------>-<-------------------D | 1791 |
| SCN1A | ------------------------------>-<----------KG-------K | 2009 |
| SCN2A | ------------------------------>-<----------KGKDIRESKK | 2005 |
| SCN3A | ------------------------------>-<----------KGKEVRENQK | 2000 |
| SCN4A | ------------------------------>-<----------VRPGVKESLV | 1836 |
| SCN5A | ------------------------------>-<------DFPPSPDRDRESIV | 2016 |
| SCN7A | ------------------------------>-<---------------IQSQI | 1682 |
| SCN8A | ------------------------------>-<----------RQKEVRESKC | 1980 |
| SCN9A | ------------------------------>-<----------KGKDSKESKK | 1977 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.R2118C | c.6352C>T | Putative Benign | SIFT: Polyphen: |