Paralogue Annotation for CACNA1C residue 2124

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2124
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 2124

No paralogue variants have been mapped to residue 2124 for CACNA1C.



CACNA1CGGEEDA----------GCV-----RARGRP>S<EEELQDSRVYVSSL2138
CACNA1A------------------------------>-<RSPSEGREHMAHRQ2261
CACNA1BNGYHCTLG-LS--------------SGGR->-<ARHSYHHPDQDHWC2340
CACNA1DGPGYSD----------E-E-----PDPGR->D<EEDLADEMICITTL2181
CACNA1ENGHYRRRR-RG-----GPG-----PGMMCG>A<VNNLLSDTEEDDKC2313
CACNA1F--LYSD----------E-E-----SILSRF>D<EEDLGDEMACVHAL1977
CACNA1G------------------------------>-<-------------P2377
CACNA1HVGDPPEKRRGLYLTVPQ-CPLEKPGSPSA->-<TPA-PG-GGADDPV2353
CACNA1IAPP--------------------PQPLPG->-<ELE-PGDAASKRKR2223
CACNA1S------------------G-----SSLGSL>D<QHQGSQETLIPPRL1873
SCN10A------------------------------>-<----TSMELIAPGP1956
SCN11A------------------------------>-<-------------D1791
SCN1A------------------------------>-<----KG-------K2009
SCN2A------------------------------>-<----KGKDIRESKK2005
SCN3A------------------------------>-<----KGKEVRENQK2000
SCN4A------------------------------>-<----VRPGVKESLV1836
SCN5A------------------------------>-<DFPPSPDRDRESIV2016
SCN7A------------------------------>-<---------IQSQI1682
SCN8A------------------------------>-<----RQKEVRESKC1980
SCN9A------------------------------>-<----KGKDSKESKK1977
cons                              > <              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Ser2124Asnc.6371G>A UnknownSIFT:
Polyphen: