No paralogue variants have been mapped to residue 229 for CACNA1C.
| CACNA1C | FIIVVVGLFSAILEQATKA-DGANALGGKG>A<GFDVKALRAFRVLRPLRLVSGVPSLQVVLN | 259 |
| CACNA1A | FVVVLTGILATVGTEF-------------->-<--DLRTLRAVRVLRPLKLVSGIPSLQVVLK | 217 |
| CACNA1B | FVVVLTGILATAGTDF-------------->-<--DLRTLRAVRVLRPLKLVSGIPSLQVVLK | 214 |
| CACNA1D | FVIVIVGLFSVILEQLTKETEGGNHSSGKS>G<GFDVKALRAFRVLRPLRLVSGVPSLQVVLN | 262 |
| CACNA1E | FIVVLSGILATAGTHFN------------->T<HVDLRTLRAVRVLRPLKLVSGIPSLQIVLK | 212 |
| CACNA1F | FIIVVVGLFSVLLEQGPGRPGDAPHTGGKP>G<GFDVKALRAFRVLRPLRLVSGVPSLHIVLN | 228 |
| CACNA1G | FFIVIAGMLEYSLDLQ-------------->-<NVSFSAVRTVRVLRPLRAINRVPSMRILVT | 202 |
| CACNA1H | FFIVVAGMMEYSLDGH-------------->-<NVSLSAIRTVRVLRPLRAINRVPSMRILVT | 221 |
| CACNA1I | FFIVMAGMVEYSLDLQ-------------->-<NINLSAIRTVRVLRPLKAINRVPSMRILVN | 200 |
| CACNA1S | FTIVFLGVFTVILEQVNVIQSHTAPMSSKG>A<GLDVKALRAFRVLRPLRLVSGVPSLQVVLN | 187 |
| SCN10A | FSVITLAYVGTAIDLR-------------->-<--GISGLRTFRVLRALKTVSVIPGLKVIVG | 237 |
| SCN11A | SIVIGIAIVSYIPGIT-------------->-<-IKLLPLRTFRVFRALKAISVVSRLKVIVG | 244 |
| SCN1A | FTVITFAYVTEFVDLG-------------->-<--NVSALRTFRVLRALKTISVIPGLKTIVG | 238 |
| SCN2A | FTVITFAYVTEFVDLG-------------->-<--NVSALRTFRVLRALKTISVIPGLKTIVG | 239 |
| SCN3A | FSVIVMAYVTEFVDLG-------------->-<--NVSALRTFRVLRALKTISVIPGLKTIVG | 238 |
| SCN4A | FSVIMMAYLTEFVDLG-------------->-<--NISALRTFRVLRALKTITVIPGLKTIVG | 241 |
| SCN5A | FSVIIMAYVSENIKLG-------------->-<--NLSALRTFRVLRALKTISVIPGLKTIVG | 241 |
| SCN7A | FSVTVFEVIIRYSPLD-------------->-<--FIPTLQTARTLRILKIIPLNQGLKSLVG | 228 |
| SCN8A | FSVIMMAYITEFVNLG-------------->-<--NVSALRTFRVLRALKTISVIPGLKTIVG | 242 |
| SCN9A | FVVIVFAYLTEFVNLG-------------->-<--NVSALRTFRVLRALKTISVIPGLKTIVG | 236 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A229S | c.685G>T | Putative Benign | SIFT: Polyphen: |