No paralogue variants have been mapped to residue 519 for CACNA1C.
| CACNA1C | ----AHR-ISKSKFSRYWRRWNRFCRRKCR>A<AVKSNVFYWLVIFLVFLNTLTIASEHYNQP | 549 |
| CACNA1A | ----SIK-SAKLENSTFFHKKERRMRFYIR>R<MVKTQAFYWTVLSLVALNTLCVAIVHYNQP | 512 |
| CACNA1B | ----SLK-SGKTESSSYFRRKEKMFRFFIR>R<MVKAQSFYWVVLCVVALNTLCVAMVHYNQP | 508 |
| CACNA1D | ----GQA-ISKSKLSRRWRRWNRFNRRRCR>A<AVKSVTFYWLVIVLVFLNTLTISSEHYNQP | 568 |
| CACNA1E | ----SIK-SAKVDGVSYFRHKERLLRISIR>H<MVKSQVFYWIVLSLVALNTACVAIVHHNQP | 501 |
| CACNA1F | ----LNK-IMKTRVCRRLRRANRVLRARCR>R<AVKSNACYWAVLLLVFLNTLTIASEHHGQP | 554 |
| CACNA1G | -------SLGPDAEPSSVLAFWRLICDTFR>K<IVDSKYFGRGIMIAILVNTLSMGIEYHEQP | 768 |
| CACNA1H | PQRRAQQRAAPGE-PGWMGRLWVTFSGKLR>R<IVDSKYFSRGIMMAILVNTLSMGVEYHEQP | 818 |
| CACNA1I | KEEEEEE-QADGA-VWLCGDVWRETRAKLR>G<IVDSKYFNRGIMMAILVNTVSMGIEHHEQP | 665 |
| CACNA1S | ----LNK-I--IQFIRHWRQWNRIFRWKCH>D<IVKSKVFYWLVILIVALNTLSIASEHHNQP | 457 |
| SCN10A | ----LTS-LSQKYLIWDCCPMWVKLKTILF>G<LVTDPFAELTITLCIVVNTIFMAMEHHGMS | 690 |
| SCN11A | ----GEN-LASKYLVWNCCPQWLCVKKVLR>T<VMTDPFTELAITICIIINTVFLAMEHHKME | 602 |
| SCN1A | ----WYK-FSNIFLIWDCSPYWLKVKHVVN>L<VVMDPFVDLAITICIVLNTLFMAMEHYPMT | 793 |
| SCN2A | ----WYK-FANMCLIWDCCKPWLKVKHLVN>L<VVMDPFVDLAITICIVLNTLFMAMEHYPMT | 784 |
| SCN3A | ----WYR-FANVFLIWDCCDAWLKVKHLVN>L<IVMDPFVDLAITICIVLNTLFMAMEHYPMT | 785 |
| SCN4A | ----WYK-CAHKVLIWNCCAPWLKFKNIIH>L<IVMDPFVDLGITICIVLNTLFMAMEHYPMT | 603 |
| SCN5A | ----WNR-LAQRYLIWECCPLWMSIKQGVK>L<VVMDPFTDLTITMCIVLNTLFMALEHYNMT | 742 |
| SCN7A | ----WYK-FAKTFLIWNCSPCWLKLKEFVH>R<IIMAPFTDLFLIICIILNVCFLTLEHYPMS | 530 |
| SCN8A | ----WYK-FANTFLIWECHPYWIKLKEIVN>L<IVMDPFVDLAITICIVLNTLFMAMEHHPMT | 778 |
| SCN9A | ----WYR-FAHKFLIWNCSPYWIKFKKCIY>F<IVMDPFVDLAITICIVLNTLFMAMEHHPMT | 758 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A519T | c.1555G>A | Putative Benign | rs371702432 | SIFT: tolerated Polyphen: possibly damaging |