Paralogue Annotation for CACNA1C residue 856

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 856
Reference Amino Acid: G - Glycine
Protein Domain: Interdomain Linker II-III


Paralogue Variants mapped to CACNA1C residue 856

No paralogue variants have been mapped to residue 856 for CACNA1C.



CACNA1C--------------------------EMPV>G<PRP---------------------------859
CACNA1ARQDPPLAEDIDNMKNNKLATAESAAPHGSL>G<HAGLPQSPAKMGNSTDPGPMLAIPAMATNP1117
CACNA1B-----------------------EKE---->-<---ATEKEAEIVEADKEKELR-NHQPREPH1027
CACNA1D--------------------------EVPA>G<PRP---------------------------865
CACNA1E------------------------------>-<---MGRVI-------S------QSEPDLSC1055
CACNA1F--------------------------EEEG>A<GGV---------------------------830
CACNA1G--------------------------NLSK>G<ERV---------------------------1236
CACNA1H--------------------------EDSC>C<LRL---------------------------1254
CACNA1I--------------------------DYTL>C<FRV---------------------------1130
CACNA1S--------------------------EIPL>S<PRP---------------------------758
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<----HQENKK------PT---------SQR960
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN5A---------------GGPEAP-----PDSR>T<WSQVSATASS------EA---------EAS1109
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G856Sc.2566G>A Putative Benignrs145549773SIFT: tolerated
Polyphen: possibly damaging