Paralogue Annotation for KCNE1 residue 6

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 6
Reference Amino Acid: T - Threonine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNE1 residue 6

No paralogue variants have been mapped to residue 6 for KCNE1.

KCNE1	--MILS---N>T<TAVTPFLTKLWQE---T------VQQGGN-	26
KCNE2	MSTLSN---F>T<QTLEDVFRRIFITYMDNW----RQNTTAEQ	34
KCNE3	METTNGTETW>Y<ESLHAVLKALNATLHSNLLCRPGPGLGPD-	40
KCNE4	---------->-<--------MLKMEPLNST----HPGTAASS	18
cons	> <

See full Alignment of Paralogues

Known Variants in KCNE1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T6N	c.17C>A	Unknown			SIFT: Polyphen:
Reports		Unknown		Novel genotype-phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy. Heart. 2015 101(4):294-301. doi: 10.1136/heartjnl-2014-306387. 25351510