Paralogue Annotation for KCNE2 residue 56

Residue details

Gene: KCNE2
Reference Sequences: LRG: LRG_291, Ensembl variant: ENST00000290310 / ENSP00000290310
Amino Acid Position: 56
Reference Amino Acid: M - Methionine
Protein Domain: Transmembrane region


Paralogue Variants mapped to KCNE2 residue 56

No paralogue variants have been mapped to residue 56 for KCNE2.



KCNE2NTTAEQEALQA-KVDAENFY--YVILYLMV>M<IGMFSFIIVAILVSTVKSKRREHSNDPYHQ86
KCNE1QQGGN-MSGLA-RRSPRSSDGKLEALYVLM>V<LGFFGFFTLGIMLSYIRSKKLEHSNDPFNV80
KCNE3GLGPD-NQTEERRASLPGR-DDNSYMYILF>V<MFLFAVTVGSLILGYTRSRKVDKRSDPYHV94
KCNE4GTAASSSPLES-RAAGGGSGNGNEYFYILV>V<MSFYGIFLIGIMLGYMKSKRREKKSSLLLL72
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNE2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.M56Vc.166A>G Putative BenignSIFT: tolerated
Polyphen: probably damaging