Paralogue Annotation for KCNE2 residue 90

Residue details

Gene: KCNE2
Reference Sequences: LRG: LRG_291, Ensembl variant: ENST00000290310 / ENSP00000290310
Amino Acid Position: 90
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus

Paralogue Variants mapped to KCNE2 residue 90

No paralogue variants have been mapped to residue 90 for KCNE2.

KCNE2	FSFIIVAILVSTVKSKRREHSNDPYHQYIV>E<D--WQEKYKSQILNL---------------	103
KCNE1	FGFFTLGIMLSYIRSKKLEHSNDPFNVYIE>S<DA-WQEKDKAYVQARVLESYRSCYVV----	109
KCNE3	FAVTVGSLILGYTRSRKVDKRSDPYHVYIK>N<------------------------------	98
KCNE4	YGIFLIGIMLGYMKSKRREKKSSLLLLYKD>E<ERLWGEAMKPLPVVSGLRSVQVPLMLNMLQ	106
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See full Alignment of Paralogues

Known Variants in KCNE2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E90G	c.269A>G	Other Cardiac Phenotype		rs199473366	SIFT: tolerated Polyphen: benign
Reports		Other Cardiac Phenotype		Amiodarone-associated macroscopic T-wave alternans and torsade de pointes unmasking the inherited long QT syndrome. Europace. 2008 10(1):112-3. 18006559