No paralogue variants have been mapped to residue 1017 for KCNH2.
| KCNH2 | --------------------RQYQELPRCP>A<PTP-SLLN----IPL-SSPGRRPRGDV-ES | 1040 |
| KCNH1 | -----------------------KSEDWNK>V<SKA-ESME----TLP-E------RTKA-S- | 869 |
| KCNH3 | --------------------PKFSFRVGQS>G<PE--CSSSPSPGPES-G----LLTVPH-GP | 869 |
| KCNH4 | --------------------PSFRFSRRPE>L<PRP-RSQA----PPT-GTRP-SPELAS-EA | 873 |
| KCNH5 | --------------------HEEKKEDWNN>V<TKA-ESMG----LLS-EDPKSSDSENS-V- | 853 |
| KCNH6 | --------------------QGHASYILEA>P<ASN-DLAL----VPI-ASETTSPGPRL-P- | 889 |
| KCNH7 | --------------------SALQRAAWGI>S<ET----------------ESDLTYGEV-EQ | 1033 |
| KCNH8 | --------------------QTFDFGSERI>R<SEP-RISP-----PLGDPEIGAAVLFI-KA | 860 |
| CNGA1 | ------------------------------>-<T----------------------------- | 690 |
| CNGA2 | ------------------------------>-<P----------------------------- | 664 |
| CNGA3 | ------------------------------>-<Q----------------------------- | 694 |
| CNGA4 | --------------------GRASQEGPPG>P<E----------------------------- | 575 |
| CNGB1 | --------------------PRTPPEPP-->-<------G------SP-PSSPPPAS------ | 1204 |
| CNGB3 | --------------------GREPEEKPLD>R<PECTA-S------PI-AVEEEPHS------ | 769 |
| HCN1 | ------QQ-------------VQQSQPPQT>Q<PQQPS-PQPQTPG---S--STPKNEVH-KS | 770 |
| HCN2 | ------A-P-------------ASPRAPR->-<---TS--------------PYGGLPAAPLA | 804 |
| HCN3 | ------PP----------ARTLHASLSRAG>R<SQ-VSLLG--PP---------P-------- | 698 |
| HCN4 | VGFTPRGGLSPPGHSPGPPRTFPSAPPRAS>G<SH-GSLLL--PPASS-P--PPPQVPQR-RG | 1070 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A1017P | c.3049G>C | Benign | SIFT: tolerated Polyphen: benign |