Paralogue Annotation for KCNH2 residue 1072

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1072
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1072

No paralogue variants have been mapped to residue 1072 for KCNH2.



KCNH2LSADMATVLQ--------------LLQRQM>T<LVPPAYSAVTTP------------------1084
KCNH1DSGITKSDLR--------------LDNVGE>A<RSPQDRSPILAEVKHSF-------------914
KCNH3VTELSEQVLQ--------------MREGLQ>S<LRQAVQLVLAPHREGP-------------C918
KCNH4ISRLNQEVSQ--------------LSRELR>H<IMGLLQARLGPP------------------915
KCNH5DSGITKSDLR--------------LDKAGE>A<RSPLEHSPIQADAKHPF-------------898
KCNH6SYGDLDDCSP--------------KHRNSS>P<RMP--HLAVATD------------------926
KCNH7MTTDIQTILQ--------------LLQKQT>T<VVPPAYSMVTAGSEYQR-------------1082
KCNH8VTTLTQEVSQ--------------LGKDMR>N<VIQLLENVLSPQQPSRFCSLHSTSVCPSRE920
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------------------------------>-<------------------------------
CNGB3------------------------------>-<------------------------------
HCN1LSASQPSLPHEVSTLISRPHPTVG----ES>L<ASIPQPVTAVPGTGLQ--------------828
HCN2LSASQPSLPHGAPGPAASTRPAS------->-<------------------------------842
HCN3LSASQPSLPQRATGDGSPGRKGS------->-<------------------------------734
HCN4ISASQPALPQDGAQTLRRASPHSSGESMAA>F<PLFPRAGGGSGGSGS---------------1131
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1072Mc.3215C>T Putative BenignSIFT:
Polyphen: