Paralogue Annotation for KCNH2 residue 1079

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1079
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1079

No paralogue variants have been mapped to residue 1079 for KCNH2.



KCNH2VLQ--------------LLQRQMTLVPPAY>S<AVTTP------------------------G1085
KCNH1DLR--------------LDNVGEARSPQDR>S<PILAEVKHSF-------------YPIPEQT921
KCNH3VLQ--------------MREGLQSLRQAVQ>L<VLAPHREGP-------------CPRAS---922
KCNH4VSQ--------------LSRELRHIMGLLQ>A<RLGPP------------------GHPAGSA922
KCNH5DLR--------------LDKAGEARSPLEH>S<PIQADAKHPF-------------YPIPEQA905
KCNH6CSP--------------KHRNSSPRMP--H>L<AVATD------------------------K927
KCNH7ILQ--------------LLQKQTTVVPPAY>S<MVTAGSEYQR-------------PIIQLMR1089
KCNH8VSQ--------------LGKDMRNVIQLLE>N<VLSPQQPSRFCSLHSTSVCPSRESLQTRTS927
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------------------------------>-<----------------------------LG1206
CNGB3------------------------------>-<----------------------------VR771
HCN1LPHEVSTLISRPHPTVG----ESLASIPQP>V<TAVPGTGLQ-----------------AG--830
HCN2LPHGAPGPAASTRPAS-------------->-<------------------------------842
HCN3LPQRATGDGSPGRKGS-------------->-<------------------------------734
HCN4LPQDGAQTLRRASPHSSGESMAAFPLFPRA>G<GGSGGSGS----------------------1131
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S1079Nc.3236G>A Putative BenignSIFT:
Polyphen: