Paralogue Annotation for KCNH2 residue 1090

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1090
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1090

No paralogue variants have been mapped to residue 1090 for KCNH2.



KCNH2P------------------------GPGPT>S<TSPLL-----PVSPLP-TLTLDSLSQVSQF1114
KCNH1EVKHSF-------------YPIPEQTLQAT>V<LEVRH-----ELKEDIKALNAKMTNIEKQL951
KCNH3HREGP-------------CPRAS-----GE>G<PCPASTSGLLQPLCVDTGASSYCLQPPAGS955
KCNH4P------------------GHPAGSAWTPD>P<PCPQL-----RP-----PCLSPCASRPPPS947
KCNH5DAKHPF-------------YPIPEQALQTT>L<QEVKH-----ELKEDIQLLSCRMTALEKQV935
KCNH6D------------------------KTLAP>S<SEQEQ-----PEGLWP-PLASPLHPLEVQG956
KCNH7GSEYQR-------------PIIQLMRTSQP>E<ASIKT-----DRSFSPSSQCPEFLDLEKSK1119
KCNH8QQPSRFCSLHSTSVCPSRESLQTRTSWSAH>Q<PCLHL-----QTGGAAYTQAQLCSSNITSD957
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------------------------LGRPEG>E<EEGPA-----EPEEHSVRIC----------1226
CNGB3------------------------VRR--->-<TVLPR-----GTSRQSLIIS----------787
HCN1GTGLQ-----------------AG----G->-<-RST--------------VP-QRVTLFRQM845
HCN2----------------------------S->-<-ST-------------PRLG-P--------850
HCN3----------------------------G->-<-SE-------------R-LP-PSGLL----745
HCN4GSGS------------------------S->-<-GGLG-----PPGRPYGAIPGQHVTLPRKT1156
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S1090Fc.3269C>T Putative BenignSIFT:
Polyphen: