Paralogue Annotation for KCNH2 residue 1102

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1102
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1102

No paralogue variants have been mapped to residue 1102 for KCNH2.



KCNH2-------GPGPTSTSPLL-----PVSPLP->T<LTLDSLSQVSQFMACEELPPGAPELPQ---1129
KCNH1-YPIPEQTLQATVLEVRH-----ELKEDIK>A<LNAKMTNIEKQLSEILRILTSRRS------963
KCNH3CPRAS-----GEGPCPASTSGLLQPLCVDT>G<ASSYCLQPPAGSVLSGTWPHPRPGPPPL--971
KCNH4-GHPAGSAWTPDPPCPQL-----RP----->P<CLSPCASRPPPSLQDTTLAEVH-CPASV--962
KCNH5-YPIPEQALQTTLQEVKH-----ELKEDIQ>L<LSCRMTALEKQVAEILKILSEKSVPQ----949
KCNH6-------KTLAPSSEQEQ-----PEGLWP->P<LASPLHPLEVQGLICG--------------960
KCNH7-PIIQLMRTSQPEASIKT-----DRSFSPS>S<QCPEFLDLEKSKLKSKESLSSGVHLNTA--1135
KCNH8ESLQTRTSWSAHQPCLHL-----QTGGAAY>T<QAQLCSSNITSDIWSVDPSSVGSSPQRT--973
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------LGRPEGEEEGPA-----EPEEHSV>R<IC----------------------------1226
CNGB3------VRR----TVLPR-----GTSRQSL>I<IS----------------------------787
HCN1----AG----G---RST------------->-<VP-QRVTLFRQMSSGAIP------PNRGVP857
HCN2----------S---ST-------------P>R<LG-P-----------------TP-AARAAA858
HCN3----------G---SE-------------R>-<LP-PSGLL-------AKP------PRTAQP754
HCN4----------S---GGLG-----PPGRPYG>A<IPGQHVTLPRKTSSGSLPPPLSLFGARATS1174
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1102Pc.3304A>C Putative BenignSIFT:
Polyphen: benign
p.Thr1102Ilec.3305C>T UnknownSIFT:
Polyphen: