Paralogue Annotation for KCNH2 residue 142

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 142
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNH2 residue 142

No paralogue variants have been mapped to residue 142 for KCNH2.

KCNH2	----------------------------SP>A<HD----------------------------	144
KCNH1	----------------------------ED>D<S-----------------------------	144
KCNH3	----------------------------GP>D<R-----------------------------	144
KCNH4	----------------------------GP>Q<G-----------------------------	145
KCNH5	----------------------------ED>D<S-----------------------------	142
KCNH6	------------------------------>-<------------------------------
KCNH7	----------------------------TP>E<RV----------------------------	144
KCNH8	----------------------------TP>E<------------------------------	143
CNGA1	----------------------------EP>E<E-----------------------------	104
CNGA2	----------------------------RP>D<S-----------------------------	93
CNGA3	----------------------------GP>D<S-----------------------------	97
CNGA4	------------------------------>-<------------------------------
CNGB1	DAHQDVSTSPQGTEVVPAYEEENKAVEKMP>R<ELSRIEEEKEDEEEEEEEEEEEEEEEVTEV	375
CNGB3	----------------------------MF>K<SLTKVNKVKPIGENNENEQS----------	23
HCN1	----------------------------GG>E<E-----------------------------	76
HCN2	----------------------------GP>A<E-----------------------------	142
HCN3	------------------------------>-<------------------------------
HCN4	----------------------------EG>G<A-----------------------------	194
cons	> <

See full Alignment of Paralogues

Known Variants in KCNH2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A142T	c.424G>A	Putative Benign			SIFT: Polyphen: