Paralogue Annotation for KCNH2 residue 144

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 144
Reference Amino Acid: D - Aspartate
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 144

No paralogue variants have been mapped to residue 144 for KCNH2.



KCNH2--------------------------SPAH>D<------------------------------144
KCNH1--------------------------EDDS>-<------------------------------144
KCNH3--------------------------GPDR>-<------------------------------144
KCNH4--------------------------GPQG>-<------------------------------145
KCNH5--------------------------EDDS>-<------------------------------142
KCNH6------------------------------>-<------------------------------
KCNH7--------------------------TPER>V<------------------------------144
KCNH8--------------------------TPE->-<------------------------------143
CNGA1--------------------------EPEE>-<------------------------------104
CNGA2--------------------------RPDS>-<------------------------------93
CNGA3--------------------------GPDS>-<------------------------------97
CNGA4------------------------------>-<------------------------------
CNGB1HQDVSTSPQGTEVVPAYEEENKAVEKMPRE>L<SRIEEEKEDEEEEEEEEEEEEEEEVTEVLL377
CNGB3--------------------------MFKS>L<TKVNKVKPIGENNENEQS------------23
HCN1--------------------------GGEE>-<------------------------------76
HCN2--------------------------GPAE>-<------------------------------142
HCN3------------------------------>-<------------------------------
HCN4--------------------------EGGA>-<------------------------------194
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D144Vc.431A>T Putative Benignrs146284716SIFT: deleterious
Polyphen: benign