Paralogue Annotation for KCNH2 residue 15

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 15
Reference Amino Acid: L - Leucine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNH2 residue 15

No paralogue variants have been mapped to residue 15 for KCNH2.

KCNH2	--------------RR----G-HVAPQNTF>L<DTI---IR----KFEGQSRK----------	28
KCNH1	--------------RR----G-LVAPQNTF>L<ENI---VR----RS--NDTN----------	29
KCNH3	--------------MR----G-LLAPQNTF>L<DTI---AT----RFDGTHSN----------	28
KCNH4	--------------MK----G-LLAPQNTF>L<DTI---AT----RFDGTHSN----------	28
KCNH5	--------------KR----G-LVAPQNTF>L<ENI---VR----RS--SESS----------	27
KCNH6	--------------RR----G-HVAPQNTY>L<DTI---IR----KFEGQSRK----------	28
KCNH7	--------------RR----G-HVAPQNTF>L<GTI---IR----KFEGQNKK----------	28
KCNH8	--------------MK----G-LLAPQNTF>L<DTI---AT----RFDGTHSN----------	28
CNGA1	--------------SMK---NNIINTQQSF>V<TMPNVIVP----DIEKE------------I	31
CNGA2	--------------K--------TNGVK-->-<-----SSP----AN----------------	14
CNGA3	-----------------------INTQY-->-<-----SHP----SRTH-------------L	16
CNGA4	------------------------------>-<------------------------------
CNGB1	ESMPPEESFKEEEVAV-----ADPSPQETK>E<AAL---TSTISLRAQGAEISEMNSPSRRVL	103
CNGB3	------------------------------>-<------------------------------
HCN1	--------------G--------------->-<-------------GKPNS------------	9
HCN2	------------------------------>-<RG-----G----GGRPGE------------	12
HCN3	--------------E--------------->-<-------------QRPAA------------	9
HCN4	--------------LPPSMRKRLYSLPQQV>G<AK-----A----WIMDEE------------	29
cons	> <

See full Alignment of Paralogues

Known Variants in KCNH2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.Leu15Gln	c.44T>A	Unknown			SIFT: Polyphen: