Paralogue Annotation for KCNH2 residue 198

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 198
Reference Amino Acid: V - Valine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 198

No paralogue variants have been mapped to residue 198 for KCNH2.



KCNH2PALLALTARESSVRSGGAGGAGAPGAVVVD>V<DLTPAAPSSESLALDEVTAMDNHVAGLGPA228
KCNH1------------------------------>-<------------------------------
KCNH3R----------------------------->-<------------------------------153
KCNH4N----------------------------->-<------------------------------154
KCNH5------------------------------>-<------------------------------
KCNH6LSQSFLGSEGSHGRPGGPG----------->-<----------------------------PG169
KCNH7PGLRVLTYRKQSLPQEDPD------VVVID>S<----SKHSDDSVAMKHFKSPTKESCSPSEA213
KCNH8K----------------------------->-<------------------------------149
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1WEEVGEEAKKEAEEKAKEEAEEVAEEEAEK>E<PQDWAETKEEPEAEAEAASSGVPATKQHPE466
CNGB3--TTAQEENKGEEKSLKTKSTPVTSEEPHT>N<IQDKLSKKN---------SSGDLTTNPDPQ89
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V198Lc.592G>C Putative BenignSIFT:
Polyphen: