Paralogue Annotation for KCNH2 residue 199

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 199
Reference Amino Acid: D - Aspartate
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 199

No paralogue variants have been mapped to residue 199 for KCNH2.



KCNH2ALLALTARESSVRSGGAGGAGAPGAVVVDV>D<LTPAAPSSESLALDEVTAMDNHVAGLGPAE229
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6SQSFLGSEGSHGRPGGPG------------>-<---------------------------PG-169
KCNH7GLRVLTYRKQSLPQEDPD------VVVIDS>-<---SKHSDDSVAMKHFKSPTKESCSPSEAD214
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1EEVGEEAKKEAEEKAKEEAEEVAEEEAEKE>P<QDWAETKEEPEAEAEAASSGVPATKQHPEV467
CNGB3-TTAQEENKGEEKSLKTKSTPVTSEEPHTN>I<QDKLSKKN---------SSGDLTTNPDPQN90
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D199Ac.596A>C Putative BenignSIFT:
Polyphen: