Paralogue Annotation for KCNH2 residue 200

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 200
Reference Amino Acid: L - Leucine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 200

No paralogue variants have been mapped to residue 200 for KCNH2.



KCNH2LLALTARESSVRSGGAGGAGAPGAVVVDVD>L<TPAAPSSESLALDEVTAMDNHVAGLGPAEE230
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6QSFLGSEGSHGRPGGPG------------->-<--------------------------PG--169
KCNH7LRVLTYRKQSLPQEDPD------VVVIDS->-<--SKHSDDSVAMKHFKSPTKESCSPSEADD215
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1EVGEEAKKEAEEKAKEEAEEVAEEEAEKEP>Q<DWAETKEEPEAEAEAASSGVPATKQHPEVQ468
CNGB3TTAQEENKGEEKSLKTKSTPVTSEEPHTNI>Q<DKLSKKN---------SSGDLTTNPDPQNA91
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L200Qc.599T>A Putative BenignSIFT:
Polyphen: